What Is Collagen?

Collagen (KOL-uh-jin) is a protein in the body. Different types of collagen are in many body parts, including hair, skin, nails, bones, ligaments, tendons, cartilage, blood vessels, and intestines.

What Does Collagen Do?

Collagen has many different roles in the body. It:

• helps make bones strong
• lets the skin and tendons stretch
• helps with healing after an injury

What Are the Different Kinds of Collagen?

Our bodies have many different kinds of collagen. Most of it is type I collagen, found in bones and tendons. But we also have:

• type II collagen, found in cartilage (the bendable material in the nose, ears, and joints)
• type III collagen, found in skin, the lining of blood vessels, and the intestines

What Problems Can Happen With Collagen?

Depending on which type of collagen is affected, problems can include:

• osteogenesis imperfecta (also called brittle bone disease), caused by a problem with type I collagen
• Elhers-Danlos syndrome (which leads to stretchy skin and joints), often caused by a problem with type IV collagen

The symptoms of problems with collagen can vary greatly. Some people have very mild symptoms, while others have moderate or more severe symptoms.

How Do Problems With Collagen Happen?

Most kids with a collagen problem have it because they inherited a gene from one or both of their parents. But sometimes it happens in a child without a family history.

What Else Should I Know?

Collagen has many important roles in the body. A child who has a collagen problem may need medical care throughout life.

To help your child get the best care possible:

• Find out all you can about your child's medical condition.
• If your child is old enough, talk about the problem. Use simple words and let your child ask questions. Be positive, but honest.
• Take your child to all medical visits.
• Follows the health care provider's treatment recommendations.